Introduction: Food additives (AA) are ingredients that are added to foods to modify their physical and chemical characteristics. Approximately 1,000 AA are used under the “Generally Recognized as Safe” designation without approval from the US Food and Drug Administration. There is evidence that some AA can be potentially toxic to health. The person in charge of regulating AA worldwide is the Food and Agriculture Organization of the United Nations and the World Health Organization, through the Codex Alimentarius Commission. However, in Mexico there are no studies on the toxicity of AA in the population, given the impossibility of estimating its consumption taking the “Admissible Daily Intake” as a reference (IDA).