Health Canada’s Food Directorate assessed L-alpha-glycerylphosphorylcholine (AGPC) for safety as a supplemental ingredient in foods, based on publicly available information. The Food Directorate concluded that AGPC can be considered a source of supplemental choline and will thus be subject to the conditions of use for choline set out in the List of Permitted Supplemental Ingredients. Consequently, Health Canada plans to allow the use of AGPC as a supplemental ingredient in foods under certain conditions. The conditions are outlined in the Notice of Proposal.