EFSA’s Methodology and Scientific Support (MESE) Unit has launched an open consultation on the draft Scientific Opinion on an Acceptable Daily Intake (ADI) for exposure to copper, in response to a mandate by the European Commission (M-2020-0087). The approach applied in this assessment is the first case of a compound that falls within the context of the 2021 EFSA Statement on “Establishing health-based guidance values for regulated products that are also nutrients”. The aim of this public consultation is to collect constructive input on the establishment of an ADI for copper, within the context of the 2021 EFSA Statement and other relevant EFSA Guidance.