The U.S. Food and Drug Administration removed 5-alpha-hydroxy-laxogenin and octopamine from the Dietary Supplement Ingredient Advisory List because, based on available information, the ingredients fall into one of the three categories described:

1. The ingredient appears to be excluded from use in a dietary supplement;
2. The ingredient does not appear to be a dietary ingredient and does not appear to be either an approved food additive or generally recognized as safe for use; or
3. The ingredient appears to be subject to the requirement for pre-market notification, but the requirement has not been satisfied.

Although this list reflects ingredients for which the FDA has made a preliminary assessment, it is not an exhaustive list of ingredients that may or may not be lawfully included in dietary supplements. Ingredients may be added to or removed from this list as the FDA continues its evaluation.