The National Health Surveillance Agency (ANVISA in Portuguese) Anvisa has published updated versions of guidelines for evaluating the mutagenic potential, carcinogenic potential, neurotoxicity and reproductive toxicity of pesticides.

The guidelines provide guidance on the toxicological evaluation of pesticides, which encompasses the assessment of various outcomes and is carefully conducted by the Agency, both during product registration and during a possible reanalysis.

In addition, the guides express ANVISA’s understanding of best practice in relation to procedures, routines and methods considered appropriate to meet the technical or administrative requirements mandated by the Agency’s legislative and regulatory frameworks.

Guide 66/2023 – version 2 – Guide to the Assessment of the Mutagenic Potential of Pesticides

Guide 67/2023 – version 2 – Guide for the Evaluation of the Reproductive Toxicity Potential of Pesticides

Guide 68/2023 – version 2 – Guide for the Evaluation of the Carcinogenic Potential of Pesticides

Guide 69/2023 – version 2 – Guide for the Evaluation of Neurotoxicity Associated with Pesticides